- Editorial Policies
- Appeals and Complaints
- Authorship Principles
- Dual Use of Research Content
- Competing Interests
- Complementary and Alternative Medicine Standards for Research
- Corrections and Retractions
- Data Availability Statement
- Ethical responsibilities of authors
- Harmful Research Content
- Informed Consent
- Portable Peer Review
- Predatory Journals and References
- Preprint Sharing
- Policy, Process and Guidance for Peer Reviewers
- Removal of Published Content
- Research involving animals, and their data or biological material
- Research Involving Human Participants, their Data or Biological Material
- Research Involving Human Embryos
- Research Involving Palaeontological and Geological Material
- Sex and Gender in Research (SAGER Guidelines)
- Standards of Reporting
- Utilization of plants, algae, fungi
Research involving human embryos, gametes, and stem cells
Manuscripts that report experiments involving the use of human embryos and gametes, human embryonic stem cells and related materials, and clinical applications of stem cells must include confirmation that all experiments were performed in accordance with relevant guidelines and regulations (See also Research involving human participants and/or animals)
The manuscript should include an ethics statement identifying the institutional and/or national research ethics committee (including the name of the ethics committee) approving the experiments and describing any relevant details. Authors should confirm that informed consent (See also Informed consent) was obtained from all recipients and/or donors of cells or tissues, where necessary, and describe the conditions of donation of materials for research, such as human embryos or gametes. Copies of approval and redacted consent documents may be requested by the Journal.
We encourage authors to follow the principles laid out in the 2016 ISSCR Guidelines for Stem Cell Research and Clinical Translation.
In deciding whether to publish papers describing modifications of the human germline, the Journal is guided by safety considerations, compliance with applicable regulations, as well as the status of the societal debate on the implications of such modifications for future generations. In case of concerns regarding a particular type of study the Journal may seek the advice from the Springer Nature Research Integrity Group.
The decision to publish a paper is the responsibility of the Editor-in-Chief of the Journal.